My own family history is not promising in old age. Most likely, I might expect to either pop my clogs in my 60s or get Alzheimers in my 70s, looking at my parents and grandfathers, although my grandmothers and most of my uncles and aunts have done a bit better than this. And, of course, with life expectancy generally trending upwards slowly over time, we might hope for better outcomes than our parents in any event, with a bit of luck and good self-care.